5TBW
Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome
This is a non-PDB format compatible entry.
Summary for 5TBW
Entry DOI | 10.2210/pdb5tbw/pdb |
Descriptor | 25S ribosomal RNA, 60S ribosomal protein L8-A, 60S ribosomal protein L9-A, ... (87 entities in total) |
Functional Keywords | protein translation inhibitor, complex, ribosome |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) More |
Total number of polymer chains | 159 |
Total formula weight | 6294772.15 |
Authors | Konst, Z.A.,Szklarski, A.R.,Pellegrino, S.,Michalak, S.E.,Meyer, M.,Zanette, C.,Cencic, R.,Nam, S.,Horne, D.A.,Pelletier, J.,Mobley, D.L.,Yusupova, G.,Yusupov, M.,Vanderwal, C.D. (deposition date: 2016-09-13, release date: 2017-07-26, Last modification date: 2024-01-17) |
Primary citation | Konst, Z.A.,Szklarski, A.R.,Pellegrino, S.,Michalak, S.E.,Meyer, M.,Zanette, C.,Cencic, R.,Nam, S.,Voora, V.K.,Horne, D.A.,Pelletier, J.,Mobley, D.L.,Yusupova, G.,Yusupov, M.,Vanderwal, C.D. Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides. Nat Chem, 9:1140-1149, 2017 Cited by PubMed: 29064494DOI: 10.1038/nchem.2800 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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