5T6U
Crystal structure of mouse cathepsin K at 2.9 Angstroms resolution.
Summary for 5T6U
Entry DOI | 10.2210/pdb5t6u/pdb |
Descriptor | Cathepsin K, SULFATE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | cathepsin k, n-acetyl-d-glucosamine, hydrolase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 23957.79 |
Authors | Law, S.,Aguda, A.,Nguyen, N.,Brayer, G.,Bromme, D. (deposition date: 2016-09-01, release date: 2017-01-18, Last modification date: 2023-10-04) |
Primary citation | Law, S.,Andrault, P.M.,Aguda, A.H.,Nguyen, N.T.,Kruglyak, N.,Brayer, G.D.,Bromme, D. Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib. Biochem. J., 474:851-864, 2017 Cited by PubMed: 28049758DOI: 10.1042/BCJ20160985 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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