5T6K

Crystal Structure of TgCDPK1 From Toxoplasma Gondii complexed with GW780159X

Summary for 5T6K

• Entry DOI: 10.2210/pdb5t6k/pdb
• Related: 3KU2 5T6A 5T6I
• Descriptor: Calmodulin-domain protein kinase 1, 4-(3-chlorophenyl)-5-(1,5-naphthyridin-2-yl)-1,3-thiazol-2-amine, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: structural genomics consortium, sgc, cdpks, serine/threonine protein kinase, nucleotide-binding, transferase
• Biological source: Toxoplasma gondii
• Total number of polymer chains: 1
• Total formula weight: 59872.22

Authors

Jiang, D.Q.,Tempel, W.,Walker, J.R.,El Bakkouri, M.,Loppnau, P.,Graslund, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Hui, R.,Lovato, D.V.,Osman, K.T.,Structural Genomics Consortium (SGC) (deposition date: 2016-09-01, release date: 2016-11-02, Last modification date: 2023-10-04)

• Primary citation: Jiang, D.Q.,Tempel, W.,Walker, J.R.,El Bakkouri, M.,Loppnau, P.,Graslund, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Hui, R.,Lovato, D.V.,Osman, K.T.; Crystal Structure of CDPK1 from toxoplasma gondii complexed with SGC-1-19; to be published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)