5T4X

CRYSTAL STRUCTURE OF PDE6D IN APO-STATE

Summary for 5T4X

Entry DOI	10.2210/pdb5t4x/pdb
Descriptor	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (2 entities in total)
Functional Keywords	immunoglobulin-like beta sandwitch, pde6 delta, farnesyl, lipid binding protein, prenyl binding protein, geranylgeranyl, transport protein, phosphodiesterase 6, rhodopsin, membrane dissociation, apo-state, membrane trafficking, cellular trafficking, rhodopsin kinase, ras-gtpase
Biological source	Mus musculus (Mouse)
Cellular location	Cytoplasm, cytosol : O55057
Total number of polymer chains	1
Total formula weight	19540.31
Authors	Qureshi, B.M.,Schmidt, A.,Scheerer, P. (deposition date: 2016-08-30, release date: 2018-01-10, Last modification date: 2024-01-17)
Primary citation	Qureshi, B.M.,Schmidt, A.,Behrmann, E.,Burger, J.,Mielke, T.,Spahn, C.M.T.,Heck, M.,Scheerer, P. Mechanistic insights into the role of prenyl-binding protein PrBP/ delta in membrane dissociation of phosphodiesterase 6. Nat Commun, 9:90-90, 2018 Cited by PubMed: 29311697 DOI: 10.1038/s41467-017-02569-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation