5T2Y
Crystal Structure of C. jejuni PglD in complex with 5-methyl-4-(methylamino)-2-phenethylthieno[2,3-d]pyrimidine-6-carboxylic acid
Summary for 5T2Y
Entry DOI | 10.2210/pdb5t2y/pdb |
Related | 3BSS 3BSY |
Descriptor | UDP-N-acetylbacillosamine N-acetyltransferase, 5-methyl-4-(methylamino)-2-(2-phenylethyl)thieno[2,3-d]pyrimidine-6-carboxylic acid, GLYCEROL, ... (5 entities in total) |
Functional Keywords | campylobacter jejuni bacterial acetyltransferase inhibitor complex, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) |
Total number of polymer chains | 2 |
Total formula weight | 43867.26 |
Authors | De Schutter, J.W.,Imperiali, B. (deposition date: 2016-08-24, release date: 2017-02-22, Last modification date: 2024-03-06) |
Primary citation | De Schutter, J.W.,Morrison, J.P.,Morrison, M.J.,Ciulli, A.,Imperiali, B. Targeting Bacillosamine Biosynthesis in Bacterial Pathogens: Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter jejuni. J. Med. Chem., 60:2099-2118, 2017 Cited by PubMed: 28182413DOI: 10.1021/acs.jmedchem.6b01869 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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