5T1V
Crystal structure of Zika virus NS2B-NS3 protease in apo-form.
Summary for 5T1V
Entry DOI | 10.2210/pdb5t1v/pdb |
Descriptor | NS2B-NS3 protease,NS2B-NS3 protease (1 entity in total) |
Functional Keywords | hydrolase, peptidase s7, flavivirus ns3 serine protease., structural genomics, center for structural genomics of infectious diseases, csgid |
Biological source | Zika virus (ZIKV) More |
Cellular location | Protein C: Virion . Small envelope protein M: Virion membrane ; Multi-pass membrane protein . Envelope protein E: Virion membrane ; Multi-pass membrane protein . Non-structural protein 1: Secreted . Non-structural protein 2A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease subunit NS2B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side : Q32ZE1 |
Total number of polymer chains | 2 |
Total formula weight | 58145.50 |
Authors | Nocadello, S.,Light, S.H.,Minasov, G.,Shuvalova, L.,Cardona-Correa, A.A.,Ojeda, I.,Vargas, J.,Johnson, M.E.,Lee, H.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2016-08-22, release date: 2016-09-07, Last modification date: 2023-10-04) |
Primary citation | Nocadello, S.,Light, S.H.,Minasov, G.,Shuvalova, L.A.,Cardona-Correa, A.A.,Ojeda, I.,Vargas, J.,Johnson, M.E.,Lee, H.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases Crystal structure of Zika virus NS2B-NS3 protease in apo-form. To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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