5T1V

Crystal structure of Zika virus NS2B-NS3 protease in apo-form.

5T1V の概要

• エントリーDOI: 10.2210/pdb5t1v/pdb
• 分子名称: NS2B-NS3 protease,NS2B-NS3 protease (1 entity in total)
• 機能のキーワード: hydrolase, peptidase s7, flavivirus ns3 serine protease., structural genomics, center for structural genomics of infectious diseases, csgid
• 由来する生物種: Zika virus (ZIKV); 詳細
• 細胞内の位置: Protein C: Virion . Small envelope protein M: Virion membrane ; Multi-pass membrane protein . Envelope protein E: Virion membrane ; Multi-pass membrane protein . Non-structural protein 1: Secreted . Non-structural protein 2A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease subunit NS2B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side : Q32ZE1
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58145.50

構造登録者

Nocadello, S.,Light, S.H.,Minasov, G.,Shuvalova, L.,Cardona-Correa, A.A.,Ojeda, I.,Vargas, J.,Johnson, M.E.,Lee, H.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2016-08-22, 公開日: 2016-09-07, 最終更新日: 2023-10-04)

• 主引用文献: Nocadello, S.,Light, S.H.,Minasov, G.,Shuvalova, L.A.,Cardona-Correa, A.A.,Ojeda, I.,Vargas, J.,Johnson, M.E.,Lee, H.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases; Crystal structure of Zika virus NS2B-NS3 protease in apo-form.; To Be Published,

実験手法

X-RAY DIFFRACTION (3.1 Å)