5SYB

Crystal structure of human PHF5A

Summary for 5SYB

• Entry DOI: 10.2210/pdb5syb/pdb
• Descriptor: PHD finger-like domain-containing protein 5A, ZINC ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: core component, sf3b complex, human spliceosome, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q7RTV0
• Total number of polymer chains: 2
• Total formula weight: 25968.15

Authors

Tsai, J.H.C.,Teng, T.,Zhu, P.,Fekkes, P.,Larsen, N.A. (deposition date: 2016-08-10, release date: 2016-09-07, Last modification date: 2024-03-06)

• Primary citation: Teng, T.,Tsai, J.H.,Puyang, X.,Seiler, M.,Peng, S.,Prajapati, S.,Aird, D.,Buonamici, S.,Caleb, B.,Chan, B.,Corson, L.,Feala, J.,Fekkes, P.,Gerard, B.,Karr, C.,Korpal, M.,Liu, X.,T Lowe, J.,Mizui, Y.,Palacino, J.,Park, E.,Smith, P.G.,Subramanian, V.,Wu, Z.J.,Zou, J.,Yu, L.,Chicas, A.,Warmuth, M.,Larsen, N.,Zhu, P.; Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.; Nat Commun, 8:15522-15522, 2017; PubMed: 28541300; DOI: 10.1038/ncomms15522

Experimental method

X-RAY DIFFRACTION (1.82 Å)