5SXH
Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B
Summary for 5SXH
Entry DOI | 10.2210/pdb5sxh/pdb |
Descriptor | DNA dC->dU-editing enzyme APOBEC-3B, ZINC ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | deaminase, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 43960.40 |
Authors | Shi, K.,Kurahashi, K.,Aihara, H. (deposition date: 2016-08-09, release date: 2017-12-27, Last modification date: 2024-01-10) |
Primary citation | Shi, K.,Demir, O.,Carpenter, M.A.,Wagner, J.,Kurahashi, K.,Harris, R.S.,Amaro, R.E.,Aihara, H. Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B. Sci Rep, 7:17415-17415, 2017 Cited by PubMed: 29234087DOI: 10.1038/s41598-017-17694-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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