5SWQ
Crystal Structure of HLA-A*0201 in complex with NA231, an influenza epitope
Summary for 5SWQ
Entry DOI | 10.2210/pdb5swq/pdb |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, NA231 influenza epitope, ... (4 entities in total) |
Functional Keywords | hla-a*02:01, cross-reactivity, heterologous immunity, tcr, t cell, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted . Note=(Microbial infection) In the presence of M: P61769 |
Total number of polymer chains | 3 |
Total formula weight | 44656.60 |
Authors | Josephs, T.M.,Rossjohn, J.,Gras, S. (deposition date: 2016-08-08, release date: 2016-10-05, Last modification date: 2023-10-04) |
Primary citation | Grant, E.J.,Josephs, T.M.,Valkenburg, S.A.,Wooldridge, L.,Hellard, M.,Rossjohn, J.,Bharadwaj, M.,Kedzierska, K.,Gras, S. Lack of Heterologous Cross-reactivity toward HLA-A*02:01 Restricted Viral Epitopes Is Underpinned by Distinct alpha beta T Cell Receptor Signatures. J.Biol.Chem., 291:24335-24351, 2016 Cited by PubMed: 27645996DOI: 10.1074/jbc.M116.753988 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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