5SUS
X-ray crystallographic structure of a covalent trimer derived from A-beta 17_36. X-ray diffractometer data set. (ORN)CVF(MEA)CED(ORN)AIIGL(ORN)V.
Summary for 5SUS
Entry DOI | 10.2210/pdb5sus/pdb |
Related | 5SUR 5SUT 5SUU |
Descriptor | 16mer A-beta peptide: ORN-CYS-VAL-PHE-MEA-CYS-GLU-ASP-ORN-ALA-ILE-ILE-GLY-LEU-ORN-VAL, CHLORIDE ION, SODIUM ION, ... (4 entities in total) |
Functional Keywords | amyloid, oligomer, alzheimer's, trimer, protein fibril, de novo protein |
Biological source | Homo sapiens |
Total number of polymer chains | 4 |
Total formula weight | 7199.16 |
Authors | Kreutzer, A.G.,Yoo, S.,Nowick, J.S. (deposition date: 2016-08-03, release date: 2017-01-11, Last modification date: 2024-03-27) |
Primary citation | Kreutzer, A.G.,Yoo, S.,Spencer, R.K.,Nowick, J.S. Stabilization, Assembly, and Toxicity of Trimers Derived from A beta. J.Am.Chem.Soc., 139:966-975, 2017 Cited by PubMed: 28001392DOI: 10.1021/jacs.6b11748 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.349 Å) |
Structure validation
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