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5SHR

Crystal Structure of human phosphodiesterase 10 in complex with N-[(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)methyl]-N,2-dimethyl-5-phenyl-1,2,4-triazol-3-amine

Summary for 5SHR
Entry DOI10.2210/pdb5shr/pdb
Group depositionTo be published (G_1002229)
DescriptorcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordsphosphodiesterase, pde10, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight159481.41
Authors
Joseph, C.,Benz, J.,Flohr, A.,Rudolph, M.G. (deposition date: 2022-02-01, release date: 2022-10-19, Last modification date: 2024-04-03)
Primary citationFlohr, A.,Schlatter, D.,Kuhn, B.,Rudolph, M.G.
Crystal Structure of a human phosphodiesterase 10 complex
To be published,
Experimental method
X-RAY DIFFRACTION (1.98 Å)
Structure validation

221051

数据于2024-06-12公开中

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