5SBD

Tubulin-maytansinoid-5b-complex

Summary for 5SBD

Entry DOI	10.2210/pdb5sbd/pdb
Group deposition	T2R-TTL-maytansinoid structures (G_1002215)
Descriptor	Tubulin alpha-1B chain, GLYCEROL, IMIDAZOLE, ... (14 entities in total)
Functional Keywords	cell cycle, tubulin fold, cytoskeleton, microtubule
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	6
Total formula weight	265296.62
Authors	Marzullo, P.,Boiarska, Z.,Perez-Pena, H.,Abel, A.-C.,Alvarez-Bernad, B.,Lucena-Agell, D.,Vasile, F.,Sironi, M.,Steinmetz, M.O.,Prota, A.E.,Diaz, J.F.,Pieraccini, S.,Passarella, D. (deposition date: 2021-07-20, release date: 2021-12-08, Last modification date: 2024-05-22)
Primary citation	Marzullo, P.,Boiarska, Z.,Perez-Pena, H.,Abel, A.C.,Alvarez-Bernad, B.,Lucena-Agell, D.,Vasile, F.,Sironi, M.,Altmann, K.H.,Prota, A.E.,Diaz, J.F.,Pieraccini, S.,Passarella, D. Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders. Chemistry, 28:e202103520-e202103520, 2022 Cited by PubMed: 34788896 DOI: 10.1002/chem.202103520 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation