5SBB
Tubulin-maytansinoid-4c-complex
Summary for 5SBB
Entry DOI | 10.2210/pdb5sbb/pdb |
Group deposition | T2R-TTL-maytansinoid structures (G_1002215) |
Descriptor | Tubulin alpha-1B chain, GLYCEROL, IMIDAZOLE, ... (14 entities in total) |
Functional Keywords | cell cycle, tubulin fold, cytoskeleton, microtubule |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 6 |
Total formula weight | 265384.77 |
Authors | Marzullo, P.,Boiarska, Z.,Perez-Pena, H.,Abel, A.-C.,Alvarez-Bernad, B.,Lucena-Agell, D.,Vasile, F.,Sironi, M.,Steinmetz, M.O.,Prota, A.E.,Diaz, J.F.,Pieraccini, S.,Passarella, D. (deposition date: 2021-07-20, release date: 2021-12-08, Last modification date: 2024-05-22) |
Primary citation | Marzullo, P.,Boiarska, Z.,Perez-Pena, H.,Abel, A.C.,Alvarez-Bernad, B.,Lucena-Agell, D.,Vasile, F.,Sironi, M.,Altmann, K.H.,Prota, A.E.,Diaz, J.F.,Pieraccini, S.,Passarella, D. Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders. Chemistry, 28:e202103520-e202103520, 2022 Cited by PubMed: 34788896DOI: 10.1002/chem.202103520 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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