5SAE
PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 NendoU in complex with Z3219959731
Summary for 5SAE
Entry DOI | 10.2210/pdb5sae/pdb |
Group deposition | PanDDA analysis group deposition (G_1002199) |
Descriptor | Uridylate-specific endoribonuclease, CITRIC ACID, pyridazin-3(2H)-one, ... (4 entities in total) |
Functional Keywords | sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, nsp15, nendou, sars-cov-2, sars, covid, covid19, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 2 |
Total formula weight | 78801.49 |
Authors | Godoy, A.S.,Douangamath, A.,Nakamura, A.M.,Dias, A.,Krojer, T.,Noske, G.D.,Gawiljuk, V.O.,Fernandes, R.S.,Fairhead, M.,Powell, A.,Dunnet, L.,Aimon, A.,Fearon, D.,Brandao-Neto, J.,Skyner, R.,von Delft, F.,Oliva, G. (deposition date: 2021-05-19, release date: 2021-06-09, Last modification date: 2024-05-22) |
Primary citation | Godoy, A.S.,Nakamura, A.M.,Douangamath, A.,Song, Y.,Noske, G.D.,Gawriljuk, V.O.,Fernandes, R.S.,Pereira, H.D.M.,Oliveira, K.I.Z.,Fearon, D.,Dias, A.,Krojer, T.,Fairhead, M.,Powell, A.,Dunnet, L.,Brandao-Neto, J.,Skyner, R.,Chalk, R.,Bajusz, D.,Bege, M.,Borbas, A.,Keseru, G.M.,von Delft, F.,Oliva, G. Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res., 2023 Cited by PubMed: 37115000DOI: 10.1093/nar/gkad314 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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