5RKM

PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z2017168803

Summary for 5RKM

• Entry DOI: 10.2210/pdb5rkm/pdb
• Group deposition: PanDDA analysis group deposition (G_1002162)
• Descriptor: PH-interacting protein, (2S)-2-[(3-fluoropyridin-2-yl)(methyl)amino]propan-1-ol (3 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, fragment-based drug design, sampl7, protein binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 17812.07

Authors

Grosjean, H.,Aimon, A.,Krojer, T.,Talon, R.,Douangamath, A.,Koekemoer, L.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,von Delft, F.,Biggin, P.C. (deposition date: 2020-06-02, release date: 2020-06-17, Last modification date: 2024-03-06)

• Primary citation: Grosjean, H.,Aimon, A.,Krojer, T.,Talon, R.,Douangamath, A.,Koekemoer, L.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,von Delft, F.,Biggin, P.C.; PanDDA analysis group deposition of ground-state model; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.28 Å)