5RHA
PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen -- Crystal Structure of SARS-CoV-2 main protease in complex with Z147647874 (Mpro-x2779)
Summary for 5RHA
Entry DOI | 10.2210/pdb5rha/pdb |
Group deposition | PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen (G_1002155) |
Descriptor | 3C-like proteinase, 1-{4-[(thiophen-2-yl)methyl]piperazin-1-yl}ethan-1-one, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 1 |
Total formula weight | 34362.40 |
Authors | Fearon, D.,Owen, C.D.,Douangamath, A.,Lukacik, P.,Powell, A.J.,Strain-Damerell, C.M.,Resnick, E.,Krojer, T.,Gehrtz, P.,Wild, C.,Aimon, A.,Brandao-Neto, J.,Carbery, A.,Dunnett, L.,Skyner, R.,Snee, M.,London, N.,Walsh, M.A.,von Delft, F. (deposition date: 2020-05-15, release date: 2020-05-27) |
Primary citation | Fearon, D.,Owen, C.D.,Douangamath, A.,Lukacik, P.,Powell, A.J.,Strain-Damerell, C.M.,Resnick, E.,Krojer, T.,Gehrtz, P.,Wild, C.,Aimon, A.,Brandao-Neto, J.,Carbery, A.,Dunnett, L.,Skyner, R.,Snee, M.,London, N.,Walsh, M.A.,von Delft, F. PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
Download full validation report