5R4E

PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with RZ201

Summary for 5R4E

• Entry DOI: 10.2210/pdb5r4e/pdb
• Group deposition: PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening (G_1002118)
• Descriptor: ATPase family AAA domain-containing protein 2, (5R)-5-[(4-fluorophenyl)methyl]-5-(2-hydroxyethyl)-3-(2-methoxyethyl)imidazolidine-2,4-dione, SULFATE ION, ... (5 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16077.08

Authors

Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. (deposition date: 2020-02-21, release date: 2020-04-08, Last modification date: 2024-03-06)

• Primary citation: Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F.; PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.83 Å)