5R4E
PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with RZ201
Summary for 5R4E
Entry DOI | 10.2210/pdb5r4e/pdb |
Group deposition | PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening (G_1002118) |
Descriptor | ATPase family AAA domain-containing protein 2, (5R)-5-[(4-fluorophenyl)methyl]-5-(2-hydroxyethyl)-3-(2-methoxyethyl)imidazolidine-2,4-dione, SULFATE ION, ... (5 entities in total) |
Functional Keywords | sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 16077.08 |
Authors | Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. (deposition date: 2020-02-21, release date: 2020-04-08, Last modification date: 2024-03-06) |
Primary citation | Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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