5QYD

PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry E05a

5QYD の概要

• エントリーDOI: 10.2210/pdb5qyd/pdb
• Group deposition: PanDDA analysis of F2X-Entry vs. Aar2/RNaseH (G_1002115)
• 分子名称: Pre-mRNA-splicing factor 8, A1 cistron-splicing factor AAR2, 2-(2-methylphenyl)acetamide, ... (6 entities in total)
• 機能のキーワード: fragmax, fragmaxapp, fragment screening, rnaseh like domain, vhs like domain, u5 snrnp assembly, splicing, f2x-entry
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 66224.42

構造登録者

Weiss, M.S.,Wollenhaupt, J.,Metz, A.,Barthel, T.,Lima, G.M.A.,Heine, A.,Mueller, U.,Klebe, G. (登録日: 2020-02-12, 公開日: 2020-06-10, 最終更新日: 2024-03-06)

• 主引用文献: Wollenhaupt, J.,Metz, A.,Barthel, T.,Lima, G.M.A.,Heine, A.,Mueller, U.,Klebe, G.,Weiss, M.S.; F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.; Structure, 28:694-706.e5, 2020; PubMed: 32413289; DOI: 10.1016/j.str.2020.04.019

実験手法

X-RAY DIFFRACTION (1.67 Å)