5QXV
PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with PC631
Summary for 5QXV
Entry DOI | 10.2210/pdb5qxv/pdb |
Group deposition | PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening (G_1002118) |
Descriptor | ATPase family AAA domain-containing protein 2, (3aR,10R,10aR,11aR)-1,2,3,5,10,10a,11,11a-octahydro-3a,10-ethanopyrrolo[3',4':4,5]pyrrolo[1,2-b]isoquinolin-13-one, SULFATE ION, ... (5 entities in total) |
Functional Keywords | sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 16145.22 |
Authors | Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. (deposition date: 2020-02-11, release date: 2020-04-08, Last modification date: 2024-03-06) |
Primary citation | Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
Download full validation report