5QXV

PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with PC631

Summary for 5QXV

• Entry DOI: 10.2210/pdb5qxv/pdb
• Group deposition: PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening (G_1002118)
• Descriptor: ATPase family AAA domain-containing protein 2, (3aR,10R,10aR,11aR)-1,2,3,5,10,10a,11,11a-octahydro-3a,10-ethanopyrrolo[3',4':4,5]pyrrolo[1,2-b]isoquinolin-13-one, SULFATE ION, ... (5 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16145.22

Authors

Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. (deposition date: 2020-02-11, release date: 2020-04-08, Last modification date: 2024-03-06)

• Primary citation: Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F.; PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.74 Å)