5QXI
PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with PC587
Summary for 5QXI
Entry DOI | 10.2210/pdb5qxi/pdb |
Group deposition | PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening (G_1002118) |
Descriptor | ATPase family AAA domain-containing protein 2, (4R,4aS,7aS,9S)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3',4':5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol, (4R,4aR,7aS,9R)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3',4':5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol, ... (6 entities in total) |
Functional Keywords | sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 16299.39 |
Authors | Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. (deposition date: 2020-02-11, release date: 2020-04-08, Last modification date: 2024-03-06) |
Primary citation | Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
Download full validation report