5QIO
Covalent fragment group deposition -- Crystal Structure of OUTB2 in complex with P11
Summary for 5QIO
Entry DOI | 10.2210/pdb5qio/pdb |
Group deposition | Covalent fragment group deposition (G_1002053) |
Descriptor | Ubiquitin thioesterase OTUB2, UNKNOWN LIGAND, (1S,2S)-N'-(chloroacetyl)-2-phenylcyclopropane-1-carbohydrazide, ... (4 entities in total) |
Functional Keywords | sgc - diamond i04-1 fragment screening, xchemexplorer, protease otub2, deubiquitinating enzyme otub2, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 26614.71 |
Authors | Sethi, R.,Douangamath, A.,Resnick, E.,Bradley, A.R.,Collins, P.,Brandao-Neto, J.,Talon, R.,Krojer, T.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,London, N.,von Delft, F. (deposition date: 2018-08-10, release date: 2019-12-18, Last modification date: 2024-03-06) |
Primary citation | Sethi, R.,Douangamath, A.,Resnick, E.,Bradley, A.R.,Collins, P.,Brandao-Neto, J.,Talon, R.,Krojer, T.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,London, N.,von Delft, F. Covalent fragment group deposition To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.46 Å) |
Structure validation
Download full validation report