5QCF
Crystal structure of human Cathepsin-S with bound ligand
Summary for 5QCF
Entry DOI | 10.2210/pdb5qcf/pdb |
Group deposition | Ligand binding to Cathepsin S (G_1002040) |
Descriptor | Cathepsin S, N-benzyl-1-{2-chloro-5-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]phenyl}methanamine, SULFATE ION, ... (5 entities in total) |
Functional Keywords | d3r, cathepsin s, ligand docking, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 25397.33 |
Authors | Bembenek, S.D.,Ameriks, M.K.,Mirzadegan, T.,Yang, H.,Shao, C.,Burley, S.K. (deposition date: 2017-08-04, release date: 2017-12-20, Last modification date: 2024-10-23) |
Primary citation | Bembenek, S.D.,Ameriks, M.K.,Mirzadegan, T.,Yang, H.,Shao, C.,Burley, S.K. Crystal structure of human Cathepsin-S with bound ligand To be published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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