5PWC

PanDDA analysis group deposition -- Crystal Structure of SP100 in complex with E48115b

Summary for 5PWC

• Entry DOI: 10.2210/pdb5pwc/pdb
• Group deposition: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) (G_1002024)
• Descriptor: Nuclear autoantigen Sp-100, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (7 entities in total)
• Functional Keywords: pandda, sgc - diamond i04-1 fragment screening, bromodomain, epigenetics, xchemexplorer, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus. Isoform Sp100-C: Nucleus : P23497
• Total number of polymer chains: 2
• Total formula weight: 44209.88

Authors

Pearce, N.M.,Krojer, T.,Talon, R.,Bradley, A.R.,Fairhead, M.,Sethi, R.,Wright, N.,MacLean, E.,Collins, P.,Brandao-Neto, J.,Douangamath, A.,Renjie, Z.,Dias, A.,Ng, J.,Brennan, P.E.,Cox, O.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,von Delft, F. (deposition date: 2017-02-07, release date: 2017-03-15, Last modification date: 2024-03-06)

• Primary citation: Pearce, N.M.,Krojer, T.,Bradley, A.R.,Collins, P.,Nowak, R.P.,Talon, R.,Marsden, B.D.,Kelm, S.,Shi, J.,Deane, C.M.,von Delft, F.; A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.; Nat Commun, 8:15123-15123, 2017; PubMed: 28436492; DOI: 10.1038/ncomms15123

Experimental method

X-RAY DIFFRACTION (1.549 Å)