5PA7

humanized rat COMT in complex with 6-bromo-3-chloroquinolin-8-ol

Summary for 5PA7

• Entry DOI: 10.2210/pdb5pa7/pdb
• Group deposition: Crystal Structure of COMT complex (G_1002014)
• Descriptor: Catechol O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: methyltransferase, neurotransmitter degradation, transferase
• Biological source: Rattus norvegicus (Rat)
• Cellular location: Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
• Total number of polymer chains: 2
• Total formula weight: 50486.27

Authors

Ehler, A.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-10-19, release date: 2017-11-22, Last modification date: 2024-04-03)

• Primary citation: Lerner, C.,Jakob-Roetne, R.,Groebke-Zbinden, K.,Buettelmann, B.,Rudolph, M.G.; Crystal Structure of a COMT complex; To be published,

Experimental method

X-RAY DIFFRACTION (2.12 Å)