Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5P94

humanized rat catechol O-methyltransferase in complex with 5-(4-fluorophenyl)-2,3-dihydroxy-N-[[3-[(1H-indazol-5-ylamino)methyl]phenyl]methyl]benzamide at 1.20A

Summary for 5P94
Entry DOI10.2210/pdb5p94/pdb
Group depositionCrystal Structure of COMT complex (G_1002009)
DescriptorCatechol O-methyltransferase, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywordsmethyltransferase, neurotransmitter degradation, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceRattus norvegicus (Rat)
Cellular locationIsoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
Total number of polymer chains1
Total formula weight25671.47
Authors
Ehler, A.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-08-29, release date: 2017-08-30, Last modification date: 2021-11-17)
Primary citationLerner, C.,Rudolph, M.G.
Crystal Structure of a COMT complex
To be published,
Experimental method
X-RAY DIFFRACTION (1.2 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon