5OYJ

Crystal structure of VEGFR-2 domains 4-5 in complex with DARPin D4b

5OYJ の概要

• エントリーDOI: 10.2210/pdb5oyj/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900006
• 分子名称: DARPin D4b, Vascular endothelial growth factor receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: glycoprotein receptor kinase designed ankyrin repeat protein angiogenesis, signaling protein
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 93563.33

構造登録者

Piscitelli, C.L.,Thieltges, K.M.,Markovic-Mueller, S.,Binz, H.K.,Ballmer-Hofer, K. (登録日: 2017-09-10, 公開日: 2018-03-14, 最終更新日: 2024-01-17)

• 主引用文献: Thieltges, K.M.,Avramovic, D.,Piscitelli, C.L.,Markovic-Mueller, S.,Binz, H.K.,Ballmer-Hofer, K.; Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling.; Angiogenesis, 21:533-543, 2018; PubMed: 29502220; DOI: 10.1007/s10456-018-9606-9

実験手法

X-RAY DIFFRACTION (2.38 Å)