5OUA

Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compound RKp017

5OUA の概要

• エントリーDOI: 10.2210/pdb5oua/pdb
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP dependent protein kinase inhibitor, beta-D-ribopyranose, ... (4 entities in total)
• 機能のキーワード: complex, peptidic ligand, transferase
• 由来する生物種: Cricetulus griseus (Chinese hamster); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43317.05

構造登録者

Mueller, J.M.,Heine, A.,Klebe, G. (登録日: 2017-08-23, 公開日: 2018-09-05, 最終更新日: 2020-07-29)

• 主引用文献: Mueller, J.M.,Kirschner, R.,Geyer, A.,Klebe, G.; Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage; Acs Omega, 2019; DOI: 10.1021/acsomega.8b02364

実験手法

X-RAY DIFFRACTION (1.67 Å)