5OPI
Crystal structure of the TAPBPR-MHC I peptide editing complex
Summary for 5OPI
Entry DOI | 10.2210/pdb5opi/pdb |
Descriptor | H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, TAP binding protein-like variant (3 entities in total) |
Functional Keywords | adaptive immunity, antigen processing, antigen presentation, peptide proofreading, immune system |
Biological source | Mus musculus (Mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01899 Secreted . Note=(Microbial infection) In the presence of M: P61769 |
Total number of polymer chains | 3 |
Total formula weight | 83779.87 |
Authors | Thomas, C.,Tampe, R. (deposition date: 2017-08-09, release date: 2017-10-18, Last modification date: 2024-01-17) |
Primary citation | Thomas, C.,Tampe, R. Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing. Science, 358:1060-1064, 2017 Cited by PubMed: 29025996DOI: 10.1126/science.aao6001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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