5OOH

Human biliverdin IX beta reductase: NADP/Erythrosin extra bluish ternary complex

Summary for 5OOH

Entry DOI	10.2210/pdb5ooh/pdb
Descriptor	Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (5 entities in total)
Functional Keywords	biliverdin reductase, oxidoreductase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm : P30043
Total number of polymer chains	1
Total formula weight	23819.74
Authors	Manso, J.A.,Pereira, P.J.B. (deposition date: 2017-08-07, release date: 2018-03-07, Last modification date: 2024-01-17)
Primary citation	Nesbitt, N.M.,Zheng, X.,Li, Z.,Manso, J.A.,Yen, W.Y.,Malone, L.E.,Ripoll-Rozada, J.,Pereira, P.J.B.,Mantle, T.J.,Wang, J.,Bahou, W.F. In silicoand crystallographic studies identify key structural features of biliverdin IX beta reductase inhibitors having nanomolar potency. J. Biol. Chem., 293:5431-5446, 2018 Cited by PubMed: 29487133 DOI: 10.1074/jbc.RA118.001803 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation