5OK3
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp241 and Fasudil
Summary for 5OK3
Entry DOI | 10.2210/pdb5ok3/pdb |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, UPF0418 protein FAM164A, 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, ... (4 entities in total) |
Functional Keywords | complex, peptidic ligand, adamantyle, transferase |
Biological source | Cricetulus griseus (Chinese hamster) More |
Total number of polymer chains | 2 |
Total formula weight | 43562.48 |
Authors | Mueller, J.M.,Heine, A.,Klebe, G. (deposition date: 2017-07-25, release date: 2018-08-08, Last modification date: 2023-11-15) |
Primary citation | Muller, J.,Kirschner, R.A.,Berndt, J.P.,Wulsdorf, T.,Metz, A.,Hrdina, R.,Schreiner, P.R.,Geyer, A.,Klebe, G. Diamondoid Amino Acid-Based Peptide Kinase A Inhibitor Analogues. Chemmedchem, 14:663-672, 2019 Cited by PubMed: 30677243DOI: 10.1002/cmdc.201800779 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.588 Å) |
Structure validation
Download full validation report