5OK3
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp241 and Fasudil
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 353 | 41193.7 | 1 | UniProt (P25321) Pfam (PF00069) In PDB | Cricetulus griseus (Chinese hamster) | PKA C-alpha |
| 2 | D | UPF0418 protein FAM164A | polymer | 18 | 2077.4 | 1 | UniProt (G3HK48) In PDB | Cricetulus griseus | |
| 3 | A | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE | non-polymer | 291.4 | 1 | Chemie (M77) | |||
| 4 | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A: 0 - 350 (UniProt: P25321)
D: 8 - 25 (UniProt: G3HK48)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| His -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Bw5 9 | Thr 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43271.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 291.4 | |
| All* | Total formula weight | 43562.5 |
