5OHD

Putative inactive (dormant) dimeric state of GHR transmembrane domain

Summary for 5OHD

• Entry DOI: 10.2210/pdb5ohd/pdb
• Related: 5OEK
• NMR Information: BMRB: 34164
• Descriptor: Growth hormone receptor (1 entity in total)
• Functional Keywords: dimer, ghr, growth hormone receptor, homodimer, human, receptor, transmembrane domain, jak2 tyrosine kinase, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 10290.26

Authors

Lesovoy, D.M.,Bocharov, E.V.,Bocharova, O.V.,Urban, A.S.,Arseniev, A.S. (deposition date: 2017-07-15, release date: 2018-04-11, Last modification date: 2024-07-03)

• Primary citation: Bocharov, E.V.,Lesovoy, D.M.,Bocharova, O.V.,Urban, A.S.,Pavlov, K.V.,Volynsky, P.E.,Efremov, R.G.,Arseniev, A.S.; Structural basis of the signal transduction via transmembrane domain of the human growth hormone receptor.; Biochim. Biophys. Acta, 1862:1410-1420, 2018; PubMed: 29571748; DOI: 10.1016/j.bbagen.2018.03.022

Experimental method

SOLUTION NMR