5OEK

Putative active dimeric state of GHR transmembrane domain

Summary for 5OEK

Entry DOI	10.2210/pdb5oek/pdb
NMR Information	BMRB: 34160
Descriptor	Growth hormone receptor (1 entity in total)
Functional Keywords	dimer, ghr, growth hormone receptor, homodimer, human, receptor, transmembrane domain, tyrosine kinase, membrane protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	10290.26
Authors	Lesovoy, D.M.,Bocharov, E.V.,Bocharova, O.V.,Urban, A.S.,Arseniev, A.S. (deposition date: 2017-07-08, release date: 2018-04-11, Last modification date: 2023-06-14)
Primary citation	Bocharov, E.V.,Lesovoy, D.M.,Bocharova, O.V.,Urban, A.S.,Pavlov, K.V.,Volynsky, P.E.,Efremov, R.G.,Arseniev, A.S. Structural basis of the signal transduction via transmembrane domain of the human growth hormone receptor. Biochim. Biophys. Acta, 1862:1410-1420, 2018 Cited by PubMed: 29571748 DOI: 10.1016/j.bbagen.2018.03.022 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation