5OH3

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Ethosuximide

Summary for 5OH3

• Entry DOI: 10.2210/pdb5oh3/pdb
• Descriptor: Cereblon isoform 4, ZINC ION, (3~{S})-3-ethyl-3-methyl-pyrrolidine-2,5-dione, ... (4 entities in total)
• Functional Keywords: teratogenicity, protein degradation, substrate recognition, ubiquitin ligase, unknown function
• Biological source: Magnetospirillum gryphiswaldense
• Total number of polymer chains: 3
• Total formula weight: 41589.29

Authors

Boichenko, I.,Albrecht, R.,Lupas, A.N.,Hernandez Alvarez, B.,Hartmann, M.D. (deposition date: 2017-07-14, release date: 2018-10-10, Last modification date: 2024-01-17)

• Primary citation: Boichenko, I.,Bar, K.,Deiss, S.,Heim, C.,Albrecht, R.,Lupas, A.N.,Hernandez Alvarez, B.,Hartmann, M.D.; Chemical Ligand Space of Cereblon.; Acs Omega, 3:11163-11171, 2018; PubMed: 31459225; DOI: 10.1021/acsomega.8b00959

Experimental method

X-RAY DIFFRACTION (2.1 Å)