5OGP

Metalacarborane inhibitors of Carbonic Anhydrase IX

Summary for 5OGP

Entry DOI	10.2210/pdb5ogp/pdb
Descriptor	Carbonic anhydrase 2, ZINC ION, cobaltcarborane, ... (4 entities in total)
Functional Keywords	carbonic anhydrase ix, ca inhibitor, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	29529.87
Authors	Brynda, J.,Rezacova, P.,Pospisilova, K.,Kugler, M.,Gruner, B.,Sicha, V. (deposition date: 2017-07-13, release date: 2018-08-01, Last modification date: 2024-01-17)
Primary citation	Gruner, B.,Brynda, J.,Das, V.,Sicha, V.,Stepankova, J.,Nekvinda, J.,Holub, J.,Pospisilova, K.,Fabry, M.,Pachl, P.,Kral, V.,Kugler, M.,Masek, V.,Medvedikova, M.,Matejkova, S.,Nova, A.,Liskova, B.,Gurska, S.,Dzubak, P.,Hajduch, M.,Rezacova, P. Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX. J.Med.Chem., 2019 Cited by PubMed: 31568723 DOI: 10.1021/acs.jmedchem.9b00945 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation