5OGB

Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC360.

5OGB の概要

• エントリーDOI: 10.2210/pdb5ogb/pdb
• 分子名称: Cellular retinoic acid-binding protein 2, 4-[2-(4,4-dimethyl-1-propan-2-yl-quinolin-6-yl)ethynyl]benzoic acid (3 entities in total)
• 機能のキーワード: retinoid, fluorescent, dc360, crabpii, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16058.43

構造登録者

Chisholm, D.,Tomlinson, C.,Whiting, A.,Pohl, E. (登録日: 2017-07-12, 公開日: 2018-10-24, 最終更新日: 2024-01-17)

• 主引用文献: Chisholm, D.R.,Tomlinson, C.W.E.,Zhou, G.L.,Holden, C.,Affleck, V.,Lamb, R.,Newling, K.,Ashton, P.,Valentine, R.,Redfern, C.,Erostyak, J.,Makkai, G.,Ambler, C.A.,Whiting, A.,Pohl, E.; Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways.; Acs Chem.Biol., 14:369-377, 2019; PubMed: 30707838; DOI: 10.1021/acschembio.8b00916

実験手法

X-RAY DIFFRACTION (1.8 Å)