5OE1

Im polyamide in complex with 5'CGATGTACATCG3'- hairpin polyamides studies

Summary for 5OE1

• Entry DOI: 10.2210/pdb5oe1/pdb
• NMR Information: BMRB: 34159
• Descriptor: DNA (5'-D(*CP*GP*AP*TP*GP*TP*AP*CP*AP*TP*CP*G)-3'), 1-methylimidazole-2-carboxylic acid, 4-AMINO-(1-METHYLPYRROLE)-2-CARBOXYLIC ACID, ... (6 entities in total)
• Functional Keywords: minor groove binders, dna, hairpin poyamides
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 8551.32

Authors

Padroni, G.,Parkinson, J.,Burley, G.A. (deposition date: 2017-07-07, release date: 2017-12-06, Last modification date: 2023-11-15)

• Primary citation: Padroni, G.,Parkinson, J.A.,Fox, K.R.,Burley, G.A.; Structural basis of DNA duplex distortion induced by thiazole-containing hairpin polyamides.; Nucleic Acids Res., 46:42-53, 2018; PubMed: 29194552; DOI: 10.1093/nar/gkx1211

Experimental method

SOLUTION NMR