5OCM

Imine Reductase from Streptosporangium roseum in complex with NADP+ and 2,2,2-trifluoroacetophenone hydrate

5OCM の概要

• エントリーDOI: 10.2210/pdb5ocm/pdb
• 分子名称: NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2,2,2-trifluoromethyl acetophenone hydrate, ... (5 entities in total)
• 機能のキーワード: imine, amine, nadph, oxidoreductase
• 由来する生物種: Streptosporangium roseum
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 186027.42

構造登録者

Sharma, M.,Nestl, B.,Grogan, G. (登録日: 2017-07-03, 公開日: 2018-05-16, 最終更新日: 2024-01-17)

• 主引用文献: Lenz, M.,Fademrecht, S.,Sharma, M.,Pleiss, J.,Grogan, G.,Nestl, B.M.; New imine-reducing enzymes from beta-hydroxyacid dehydrogenases by single amino acid substitutions.; Protein Eng. Des. Sel., 31:109-120, 2018; PubMed: 29733377; DOI: 10.1093/protein/gzy006

実験手法

X-RAY DIFFRACTION (1.81 Å)