5OCK

Crystal structure of ACPA E4 in complex with CEP1

Summary for 5OCK

Entry DOI	10.2210/pdb5ock/pdb
Descriptor	Human ACPA E4 Fab fragment - Light chain, Human ACPA E4 Fab fragment - Heavy chain, CEP1 peptide (from enolase), ... (4 entities in total)
Functional Keywords	anti-citrullinated protein antibody fab fragment, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	49482.07
Authors	Dobritzsch, D.,Ge, C.,Holmdahl, R. (deposition date: 2017-07-03, release date: 2018-07-04, Last modification date: 2024-01-17)
Primary citation	Ge, C.,Xu, B.,Liang, B.,Lonnblom, E.,Lundstrom, S.L.,Zubarev, R.A.,Ayoglu, B.,Nilsson, P.,Skogh, T.,Kastbom, A.,Malmstrom, V.,Klareskog, L.,Toes, R.E.M.,Rispens, T.,Dobritzsch, D.,Holmdahl, R. Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies. Arthritis Rheumatol, 71:210-221, 2019 Cited by PubMed: 30152126 DOI: 10.1002/art.40698 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation