5OAJ

Crystal structure of mutant AChBP in complex with tropisetron (T53F, Q74R, Y110A, I135S, G162E)

5OAJ の概要

• エントリーDOI: 10.2210/pdb5oaj/pdb
• 分子名称: Soluble acetylcholine receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-ETHANEDIOL, ... (6 entities in total)
• 機能のキーワード: receptor, acetylcholine binding, signaling protein
• 由来する生物種: Aplysia californica (California sea hare)
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 288185.42

構造登録者

Dawson, A.,Hunter, W.N.,de Souza, J.O.,Trumper, P. (登録日: 2017-06-22, 公開日: 2018-08-01, 最終更新日: 2024-01-17)

• 主引用文献: Dawson, A.,Trumper, P.,de Souza, J.O.,Parker, H.,Jones, M.J.,Hales, T.G.,Hunter, W.N.; Engineering a surrogate human heteromeric alpha / beta glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein.; Iucrj, 6:1014-1023, 2019; PubMed: 31709057; DOI: 10.1107/S205225251901114X

実験手法

X-RAY DIFFRACTION (2.47 Å)