5O8Q

Crystal structure of R. ruber ADH-A, mutant Y294F, W295A

Summary for 5O8Q

• Entry DOI: 10.2210/pdb5o8q/pdb
• Descriptor: Alcohol dehydrogenase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
• Functional Keywords: alcohol dehydrogenase mutant variant, nadh-dependent, zn2+-dependent, rossmann fold, oxidoreductase
• Biological source: Rhodococcus sp. M8
• Total number of polymer chains: 8
• Total formula weight: 294105.04

Authors

Dobritzsch, D.,Maurer, D.,Hamnevik, E.,Enugala, T.R.,Widersten, M. (deposition date: 2017-06-14, release date: 2017-10-11, Last modification date: 2024-01-17)

• Primary citation: Hamnevik, E.,Enugala, T.R.,Maurer, D.,Ntuku, S.,Oliveira, A.,Dobritzsch, D.,Widersten, M.; Relaxation of nonproductive binding and increased rate of coenzyme release in an alcohol dehydrogenase increases turnover with a nonpreferred alcohol enantiomer.; FEBS J., 284:3895-3914, 2017; PubMed: 28963762; DOI: 10.1111/febs.14279

Experimental method

X-RAY DIFFRACTION (2.22 Å)