5O2B

Crystal structure of WNK3 kinase domain in a diphosphorylated state and in a complex with the inhibitor PP-121

5O2B の概要

• エントリーDOI: 10.2210/pdb5o2b/pdb
• 分子名称: Serine/threonine-protein kinase WNK3, 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: wnk3, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65971.46

構造登録者

Pinkas, D.M.,Bufton, J.C.,Newman, J.A.,Borkowska, O.,Chalk, R.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.,Structural Genomics Consortium (SGC) (登録日: 2017-05-19, 公開日: 2017-06-28, 最終更新日: 2024-05-08)

• 主引用文献: Pinkas, D.M.,Daubner, G.M.,Bufton, J.C.,Bartual, S.G.,Sanvitale, C.E.,Alessi, D.R.,Bullock, A.; Crystal structure of WNK3 kinase domain in a diphosphorylated state and in a complex with the inhibitor PP-121; To Be Published,

実験手法

X-RAY DIFFRACTION (2.038 Å)