5O0Y

TLK2 kinase domain from human

Summary for 5O0Y

DescriptorSerine/threonine-protein kinase tousled-like 2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (2 entities in total)
Functional Keywordskinase, atpgs, chromatin remodelling, dna replication, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight67915.76
Authors
Mortuza, G.B.,Montoya, G. (deposition date: 2017-05-17, release date: 2018-05-30, Last modification date: 2018-07-25)
Primary citation
Mortuza, G.B.,Hermida, D.,Pedersen, A.K.,Segura-Bayona, S.,Lopez-Mendez, B.,Redondo, P.,Ruther, P.,Pozdnyakova, I.,Garrote, A.M.,Munoz, I.G.,Villamor-Paya, M.,Jauset, C.,Olsen, J.V.,Stracker, T.H.,Montoya, G.
Molecular basis of Tousled-Like Kinase 2 activation.
Nat Commun, 9:2535-2535, 2018
PubMed: 29955062 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-04941-y
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.86 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22721.0%3.4%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5o0y
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Molmil generated image of 5o0y
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