5O0W

Crystal structure of the complex between Nb474 and Trypanosoma congolense fructose-1,6-bisphosphate aldolase

Summary for 5O0W

Entry DOI	10.2210/pdb5o0w/pdb
Descriptor	Fructose-bisphosphate aldolase, Nb474, GLYCEROL, ... (4 entities in total)
Functional Keywords	complex, nanobody, aldolase, diagnosis, lyase
Biological source	Trypanosoma congolense (strain IL3000) More
Total number of polymer chains	8
Total formula weight	234587.39
Authors	Pinto, J.,Magez, S.,Sterckx, Y. (deposition date: 2017-05-17, release date: 2017-09-27, Last modification date: 2024-01-17)
Primary citation	Pinto, J.,Odongo, S.,Lee, F.,Gaspariunaite, V.,Muyldermans, S.,Magez, S.,Sterckx, Y.G. Structural basis for the high specificity of a Trypanosoma congolense immunoassay targeting glycosomal aldolase. PLoS Negl Trop Dis, 11:e0005932-e0005932, 2017 Cited by PubMed: 28915239 DOI: 10.1371/journal.pntd.0005932 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.57 Å)

Structure validation