5NZY

Crystal structure of DNA cross-link repair protein 1A in complex with Cefotaxime

Summary for 5NZY

• Entry DOI: 10.2210/pdb5nzy/pdb
• Descriptor: DNA cross-link repair 1A protein, NICKEL (II) ION, (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid, ... (4 entities in total)
• Functional Keywords: exonulcease, cephalosporin, cross-link repair, dclre1a, dna binding protein
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q6PJP8
• Total number of polymer chains: 1
• Total formula weight: 39891.69

Authors

Newman, J.A.,Aitkenhead, H.,Kupinska, K.,Burgess-Brown, N.A.,Talon, R.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2017-05-15, release date: 2017-06-14, Last modification date: 2024-01-17)

• Primary citation: Newman, J.A.,Aitkenhead, H.,Kupinska, K.,Burgess-Brown, N.A.,Talon, R.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O.; Crystal structure of DNA cross-link repair protein 1A in complex with Cefotaxime; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.551 Å)