5NVA

Substrate-bound outward-open state of a Na+-coupled sialic acid symporter reveals a novel Na+-site

Summary for 5NVA

Entry DOI	10.2210/pdb5nva/pdb
Descriptor	Putative sodium:solute symporter, SODIUM ION, N-acetyl-beta-neuraminic acid, ... (4 entities in total)
Functional Keywords	membrane transporter, sialic acid, outward-open, sodium-coupled, membrane protein
Biological source	Proteus mirabilis (strain HI4320)
Total number of polymer chains	1
Total formula weight	54631.69
Authors	Wahlgren, W.Y.,North, R.A.,Dunevall, E.,Goyal, P.,Grabe, M.,Dobson, R.,Abramson, J.,Ramaswamy, S.,Friemann, R. (deposition date: 2017-05-03, release date: 2018-04-04, Last modification date: 2020-07-29)
Primary citation	Wahlgren, W.Y.,Dunevall, E.,North, R.A.,Paz, A.,Scalise, M.,Bisignano, P.,Bengtsson-Palme, J.,Goyal, P.,Claesson, E.,Caing-Carlsson, R.,Andersson, R.,Beis, K.,Nilsson, U.J.,Farewell, A.,Pochini, L.,Indiveri, C.,Grabe, M.,Dobson, R.C.J.,Abramson, J.,Ramaswamy, S.,Friemann, R. Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+site. Nat Commun, 9:1753-1753, 2018 Cited by PubMed: 29717135 DOI: 10.1038/s41467-018-04045-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.26 Å)

Structure validation