5NUM

Engineered beta-lactoglobulin: variant F105L-L39A in complex with chlorpromazine (LG-LA-CLP)

Summary for 5NUM

Entry DOI	10.2210/pdb5num/pdb
Descriptor	Beta-lactoglobulin, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	beta-lactoglobulin, lipocalin, complex, mutant, transport protein
Biological source	Bos taurus (Bovine)
Cellular location	Secreted: P02754
Total number of polymer chains	1
Total formula weight	18570.75
Authors	Loch, J.I.,Bonarek, P.,Tworzydlo, M.,Lazinska, I.,Szydlowska, J.,Lewinski, K. (deposition date: 2017-04-30, release date: 2018-04-04, Last modification date: 2024-01-31)
Primary citation	Loch, J.I.,Bonarek, P.,Tworzydlo, M.,Lazinska, I.,Szydlowska, J.,Lipowska, J.,Rzesikowska, K.,Lewinski, K. The engineered beta-lactoglobulin with complementarity to the chlorpromazine chiral conformers. Int. J. Biol. Macromol., 114:85-96, 2018 Cited by PubMed: 29555509 DOI: 10.1016/j.ijbiomac.2018.03.074 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation