5NTN

Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds

5NTN の概要

• エントリーDOI: 10.2210/pdb5ntn/pdb
• 分子名称: Nuclear receptor ROR-gamma, Nuclear receptor-interacting protein 1, (5R,10S,13R,14R,17R)-17-((R,E)-7-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethyl-1,2,5,6,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-3,7(4H)-dione, ... (4 entities in total)
• 機能のキーワード: nuclear hormone receptor, ligand-binding domain, agonist, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Nucleus : P51449 P48552
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 130054.46

構造登録者

Kallen, J. (登録日: 2017-04-28, 公開日: 2017-06-21, 最終更新日: 2024-01-17)

• 主引用文献: Kallen, J.,Izaac, A.,Be, C.,Arista, L.,Orain, D.,Kaupmann, K.,Guntermann, C.,Hoegenauer, K.,Hintermann, S.; Structural States of ROR gamma t: X-ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds.; ChemMedChem, 12:1014-1021, 2017; PubMed: 28590087; DOI: 10.1002/cmdc.201700278

実験手法

X-RAY DIFFRACTION (1.9 Å)